The objectives of the committee are to share knowledge of processes, practices and technological goals needed for safe and productive manned missions. The committee aims to increase awareness of, space mission effects on crew and ground personnel task performance and safety, and to assess, and disseminate, effective strategies that will advance Human Performance Support Systems (HPSS) development to help the crew and ground personnel to meet mission objectives. With reference to the space medicine part of the committee field of interest, we aim to assess, and increase awareness of, spaceflight-stressor effects on crew physiological and behavioral health, and assess, and disseminate, effective crew health protection strategies. Finally, a key objective of the committee is to educate and train investigators, engineers, astronauts, and other stakeholders new to the field of human performance and health in space missions.